Explore how genomic mutations drive cancer development through the landmark Vogelstein colon cancer study and understand the genomic basis of this disease.
Explore how chemical-genetic interaction mapping is revolutionizing cancer treatment by linking tumor mutations to drug responses for personalized medicine.
Explore how data mining of the NCI-60 tumor cell line database is revolutionizing cancer drug discovery and treatment.
Discover how new indenoisoquinoline compounds target specific cancer vulnerabilities through SLFN11 and BRCA deficiency biomarkers.
Discover how network-based clustering is revolutionizing drug sensitivity prediction in cancer cell lines and advancing personalized oncology.
Exploring how cellular signaling pathways interact with epigenetic regulation to drive cancer development and the promising therapeutic approaches emerging from this research.
Explore how targeted therapies are pinpointing cancer's vulnerabilities through genetic, immune, and metabolic approaches in solid tumors.
Discover how scientists extract cancer secrets from ancient wax samples through innovative RNA profiling techniques.
New research reveals how cancer cells activate a hidden backup system—MTH1-independent 8-oxodGTPase activity—to evade targeted therapies.