Research Articles
The Chromosome Guardian: How a Fridge Mishap in Fission Yeast Revealed a Cellular Marvel
Discover how cold-sensitive mutations in the S. pombe CRM1 gene revolutionized our understanding of chromosome structure and nuclear export mechanisms.
The Two-Faced Guardian: How TP53 Mutations Shape Bladder Cancer's Destiny
Exploring the dual role of TP53 mutations in bladder cancer prognosis and treatment response, from basic biology to clinical implications.
The Genetic Rescue Mission: How a Human Gene Can Fix Bacterial Defects
Discover how the human ard gene reverses effects of mutations in E. coli rne gene, bridging evolutionary divides in genetic research.
The DNA Repair Disaster: How a Single Molecular Error Unravels Our Genome
Discover how a single amino acid mutation in DNA polymerase beta transforms a genome guardian into a cellular saboteur, causing catastrophic genomic instability.
Unlocking Cancer's Secret Switch: The KRAS G12D Mutation
Explore how scientists are using supercomputers to digitally disarm the KRAS G12D mutation, one of cancer's most notorious triggers in non-small cell lung cancer.
Catching a Culprit: How a High-Tech Sieve Hunts for Cancer's Genetic Fingerprint
Discover how Temperature Gradient Capillary Array Electrophoresis detects TP53 mutations in cancer research, advancing personalized medicine.
Cracking a Viral Code: The Genetic Flaw That Tamed a Mouse Virus
Discover how scientists identified the single genetic mutation that crippled a temperature-sensitive mouse cytomegalovirus using advanced genome sequencing techniques.