Research in Chemical Genomics

Discover cutting-edge studies and experimental approaches at the chemistry-genomics interface

Research Articles

The Cancer Cell's Double-Edged Sword: How a Common Flaw Makes Tumors Vulnerable

Discover how the loss of TGFβ signaling creates a critical vulnerability in cancer cells by forcing them to use error-prone DNA repair, making them more sensitive to therapies.

Mason Cooper

Oct 15, 2025

Popular Articles

Strategic Blueprint for Optimizing Chemogenomic Library Diversity in Modern Drug Discovery
528 views
Overcoming Class Imbalance in Drug-Target Interaction Prediction: Strategies, Benchmarks, and Future Directions
524 views
Chemogenomic Compound Libraries: Principles, Applications, and Future Directions in Drug Discovery
512 views
Automating Discovery: Advanced Strategies for High-Throughput Chemical Genetic Screens
507 views
Comparative Chemical Genomics Across Species: Unlocking Evolutionary Secrets for Drug Discovery
501 views
Next-Generation Cheminformatics: AI-Powered ADMET Prediction for Smarter Drug Discovery
494 views
Phenotypic Screening Platforms: A Comparative Analysis of Modern Technologies, AI Integration, and Clinical Success
489 views
Chemical Genomics in Drug Discovery: A Systematic Guide to Target Identification, Validation, and Therapeutic Innovation
480 views
Chemical Genetics: Basic Concepts, Methodologies, and Applications in Modern Drug Discovery
473 views
In Silico Chemogenomics: The AI-Powered Future of Drug Discovery
467 views
Next-Generation Sequencing in Chemical Sensitivity Profiling: A Comprehensive Guide for Predictive Cancer Model Development
436 views
Overexpression vs Knockdown Screens: A Comprehensive Guide for Functional Genomics and Drug Discovery
427 views
Building a Robust Comparative Chemical Genomics Pipeline for Antimicrobial Resistance Profiling
420 views
From Trial-and-Error to AI: The Evolution of the Chemical Biology Platform in Modern Drug Discovery
410 views
Optimizing NGS Workflows for Chemogenomics: A Strategic Guide to Enhance Drug Discovery
374 views
Target Families in Chemogenomics: A 2025 Guide to Multi-Target Drug Discovery
373 views
SAR Matrix Analysis: From Ligand-Target Predictions to Accelerated Drug Discovery
365 views
Validating PfATP4 as a High-Value Antimalarial Target: A Roadmap for Yeast Model Systems
353 views
Phenotypic Screening Meets Chemogenomics: A Modern Strategy for Target Deconvolution and Drug Discovery
346 views
A Scalable CRISPRi Chemical Genetics Platform: Protocol for High-Throughput Target Deconvolution and Mechanism of Action Studies
341 views

Research Tags

cancer TGFβ DNA repair