Research Articles
The Impervious Pathogen: Decoding Intrinsic Resistance Mechanisms in Pseudomonas aeruginosa
This article provides a comprehensive analysis of the intrinsic resistance mechanisms of Pseudomonas aeruginosa, a leading multidrug-resistant nosocomial pathogen.
Breaking the Barrier: Outer Membrane Permeability as the Key to Overcoming Gram-Negative Antibiotic Resistance
This article provides a comprehensive analysis of the Gram-negative bacterial outer membrane as a formidable permeability barrier and a major contributor to antibiotic resistance.
Intrinsic Resistance Unplugged: The Definitive Guide to Bacterial Efflux Pumps in Antimicrobial Defense
This article provides a comprehensive analysis of the critical role efflux pumps play as a primary mechanism of intrinsic antimicrobial resistance in bacteria.
Chromosomally Encoded Antibiotic Resistance: Molecular Mechanisms, Genomic Analysis, and Clinical Implications
This article provides a comprehensive analysis of chromosomally encoded antibiotic resistance, a critical driver of multidrug-resistant infections.
Intrinsic Antibiotic Resistance: Mechanisms, Key Bacterial Pathogens, and Research Strategies
This article provides a comprehensive analysis of bacterial species possessing intrinsic (natural) antibiotic resistance, a critical challenge in antimicrobial resistance (AMR).
The Intrinsic Resistome: Unlocking Bacterial Defenses to Forge Next-Generation Antimicrobial Strategies
This article provides a comprehensive analysis of the intrinsic resistome—the complete set of chromosomal genes that contribute to the innate antibiotic resistance of bacterial pathogens.
Intrinsic Antibiotic Resistance: Core Mechanisms, Research Methodologies, and Therapeutic Breakthroughs
This article provides a comprehensive analysis of the fundamental mechanisms underpinning intrinsic antibiotic resistance, a critical and growing challenge in clinical microbiology and drug development.
Hacking the Intrinsic Resistome: New Frontiers in Antibiotic Discovery and Resistance-Proofing Strategies
The escalating global antimicrobial resistance (AMR) crisis necessitates a paradigm shift in antibiotic discovery and development.
Comparative Analysis of Structural Variants in Mosquito Genomes: Insights for Vector Biology and Disease Control
This article provides a comprehensive analysis of structural variants (SVs) in mosquito genomes, exploring their impact on vector biology, evolution, and disease transmission mechanisms.
Cross-Species Validation of Candidate Genes for Chicken Economic Traits: From Genomic Discovery to Biomedical Application
This article synthesizes the latest genomic strategies for identifying and validating candidate genes governing economically vital traits in chickens, with direct implications for poultry science and biomedical research.