Research in Chemical Genomics

Discover cutting-edge studies and experimental approaches at the chemistry-genomics interface

Research Articles

Unraveling Cancer's Code: The Next Generation of Topoisomerase I Inhibitors

Explore the latest advances in topoisomerase I inhibitors for cancer treatment, including novel compounds like DIA-001 and their mechanisms of action.

Nora Murphy
Oct 12, 2025

Covalent Poisons of Topoisomerase II: The Molecular Scissors That Turn Fatal

Explore how covalent topoisomerase II poisons weaponize essential DNA enzymes to create powerful cancer therapies and the scientific breakthroughs driving this field.

Nolan Perry
Oct 02, 2025

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